Gene description for DEF6
Gene name DEF6 guanine nucleotide exchange factor
Gene symbol DEF6
Other names/aliases IBP
IMD87
SLAT
SWAP70L
Species Homo sapiens
 Experiment description of studies that identified DEF6 in T lymphoblast

1
Experiment ID2918
Identified moleculeprotein
Extracellular vesicle typeApoptotic bodies
MISEVLarge EVs
Identification method Mass spectrometry
PubMed ID 33661579   
OrganismHomo sapiens
Experiment descriptionPannexin-1 channel regulates nuclear content packaging into apoptotic bodies and their size
AuthorsPhan TK, Fonseka P, Tixeira R, Pathan M, Ang CS, Ozkocak DC, Mathivanan S, Poon IKH.
Journal name Proteomics
Publication year2021
SampleT lymphoblast
Sample nameJurkat T cells
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

2
Experiment ID2919
Identified moleculeprotein
Extracellular vesicle typeApoptotic bodies
MISEVLarge EVs
Identification method Mass spectrometry
PubMed ID 33661579   
OrganismHomo sapiens
Experiment descriptionPannexin-1 channel regulates nuclear content packaging into apoptotic bodies and their size
AuthorsPhan TK, Fonseka P, Tixeira R, Pathan M, Ang CS, Ozkocak DC, Mathivanan S, Poon IKH.
Journal name Proteomics
Publication year2021
SampleT lymphoblast
Sample nameJurkat T cells
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

3
Experiment ID2920
Identified moleculeprotein
Extracellular vesicle typeApoptotic bodies
MISEVLarge EVs
Identification method Mass spectrometry
PubMed ID 33661579   
OrganismHomo sapiens
Experiment descriptionPannexin-1 channel regulates nuclear content packaging into apoptotic bodies and their size
AuthorsPhan TK, Fonseka P, Tixeira R, Pathan M, Ang CS, Ozkocak DC, Mathivanan S, Poon IKH.
Journal name Proteomics
Publication year2021
SampleT lymphoblast
Sample nameJurkat T cells
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

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